Trapping and euthanasia is not an option in a no-kill society. Trap-neuter-return (TNR) is the most humane and most effective way of controlling feral cat populations. TNR has been used with success nationwide and worldwide. TNR is the preferred method of control for feral cat populations in England, Denmark, and many other forward-thinking countries. TNR is more cost-effective than trapping and killing feral cats. The average cost of sterilization is $35, while the average cost of euthanasia is $105.

A vaccinated, sterilized colony of feral cats poses no rabies threat to humans and can deter unvaccinated feral cats and wildlife from moving into the area. Raccoons, skunks, and bats are the most common carriers of rabies.

Toxoplasmosis can be caught from infected cats, but only if their feces comes in contact with a person's mouth. Toxoplasmosis in humans is most often contracted from handling or eating undercooked meat.

The number one cause of bird decline is loss of habitat and not predation by feral and outdoor cats. Biologist Peter Neville, author of Claws and Purrs, found that scavenging from trash has enabled feral cats almost to give up hunting all together.